WebMechanic’s hands. Part of antisynthetase syndrome. Condition is represented by inflammatory muscle disease, interstitial lung disease, Raynaud phenomenon, arthritis, and cutaneous manifestations, a constellation of features that are seen in about 30% of patients who have polymyositis or dermatomyositis. Not all features need to be present to ... WebDermatomyositis and polymyositis can manifest as pure muscle diseases or as part of antisynthetase syndrome, which can be associated with arthritis (usually nonerosive), fever, interstitial lung disease , hyperkeratosis of the radial aspect of the digits (mechanic's hands), and Raynaud syndrome .
Mechanic’s Hands in a Patient With Antisynthetase …
Web医脉通编译整理自:Pinal-Fernandez I, Kroodsma C T, Mammen A L. Successful treatment of refractory mechanic’s hands with ustekinumab in a patient with the antisynthetase syndrome[J]. Rheumatology, 2024, 58(7): 1307-1308. WebNov 17, 2024 · Fever and mechanic’s hands are useful clues in the differential diagnosis of autoimmune myopathy and increase the possibility of antisynthetase syndrome. At disease onset, patients with antisynthetase syndrome often present with isolated symptoms or incomplete clinical forms, mainly seronegative arthritis and interstitial lung disease. football jersey sizes chart
Mechanic
WebFeb 21, 2024 · Mechanic’s hands before ( a, b) and after ( c, d) starting treatment with ustekinumab. The antisynthetase syndrome is characterized by autoantibodies targeting … Patients with antisynthetase syndrome respond well to systemic steroidsand/or immunosuppressive agents if they only have muscle involvement. If lungs are involved, the severity and type of lung injury determine the prognosis. Older age at onset (>60 years), presence of malignancy, and negative ANA … See more Antisynthetase syndrome is a rare inflammatory muscle disease related to dermatomyositisand polymyositis. The hallmark of antisynthetase … See more The main clinical features of antisynthetase syndrome are: 1. Fever 2. Myositis (muscle inflammation) 3. Polyarthritis(inflammation in several joints) 4. … See more Some case studies have reported various malignancies occurring within 6–12 months of the diagnosis of antisynthetase syndrome. Age-appropriate screening is … See more The clinical presentation is a clue to the diagnosis of antisynthetase syndrome. Special investigations help to support the diagnosis. These may include the … See more WebAntisynthetase syndrome is characterized by the presence of some of the described antisynthetase antibodies in serum, and at least one of the following clinical signs: interstitial lung disease, inflammatory myopathy or polyarthritis. Other features that support the diagnosis can include Raynaud's phenomenon, “mechanic's hands” and fever. 2 electroplating hobby supplies